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Isopropyl Myristate
AKA “110-27-0, Isopropyl tetradecanoate, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Estergel, Deltyl Extra, propan-2-yl tetradecanoate, Kesscomir”
Emollient
Ingredient Facts
Isopropyl myristate
AKA: 110-27-0, Isopropyl tetradecanoate, Isomyst, Tetradecanoic acid, 1-methylethyl ester, Bisomel, Estergel, Deltyl Extra, Propan-2-yl tetradecanoate, Kesscomir
Emollient · Emollient · EWG: 1
Synthetic
Emollient
Fragrance
Skin Conditioner
Clean
Tetradecanoic acid, isopropyl ester
Solubility Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil; practically insoluble in glycerol, propylene glycol
Formula
C17H34O2
Mol. Weight
270.50
CAS #
110-27-0
Form
Liquid
State
Liquid
See origin →
Functions
Binding
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
Developed in the 1950s as a lightweight, non-comedogenic emollient for cosmetics and pharmaceuticals. Myristic acid comes from nutmeg and coconut oils, used in traditional Asian medicine for centuries.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Enhanced skin permeation of a new capsaicin derivative (DA-5018) from a binary vehicle system composed of isopropyl myristate and ethoxydiglycol.
Cha BJ, Lee ED, Kim WB, Chung SJ, Lee MH et al.
Archives of pharmacal research, 2001
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Final Report on the Safety Assessment of Myristyl Myristate and Isopropyl Myristate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Isopropyl Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
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Influence of the penetration enhancer isopropyl myristate on stratum corneum lipid model membranes revealed by neutron diffraction and (2)H NMR experi
Eichner A, Stahlberg S, Sonnenberger S, Lange S, Dobner B et al.
Biochimica et biophysica acta. Biomembranes, 2017
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Isopropyl Myristate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR