Isostearamidopropyl Betaine
AKA “Obazoline isab, Mackam isa, Schercotaine iab, 22W0P0GRB7, 63566-37-0, UNII-22W0P0GRB7, Isostearamidopropyl betaine [INCI], 1-Propanaminium, N-(carboxymethyl)-N, N-dimethyl-3-((1-oxoisooctadecyl)amino)-, inner salt, RefChem:149981
Surfactant
Ingredient Facts
Isostearamidopropyl betaine
AKA: Obazoline isab, Mackam isa, Schercotaine iab, 22W0P0GRB7, 63566-37-0, UNII-22W0P0GRB7, Isostearamidopropyl betaine [INCI], 1-Propanaminium, N-(carboxymethyl)-N, N-dimethyl-3-((1-oxoisooctadecyl)amino)-, Inner salt, RefChem:149981
Surfactant · Cleansing · EWG: 4
Plant-Derived
Cleanser
Skin Conditioner
Hair Care
Plant Oil
Not Clean
1-Propanaminium, N-carboxymethyl-N,N-dimethyl-3-(1-oxoisooctadecylamino)-, hydroxide, inner salt
Formula
C25H50N2O3
Mol. Weight
426.70
CAS #
63566-37-0
Form
Liquid
See origin →
Functions
Antistatic
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Foam Boosting
Locks in moisture
Traditional Use
Developed as a modern amphoteric surfactant in the latter half of the 20th century. Designed to provide gentle cleansing with conditioning benefits, often used as a replacement for harsher synthetic detergents.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR