Isostearyl Glyceryl Ether
AKA “monoisostearyl glyceryl ether, GE-IS cpd, RefChem:149991, Penetol GE-IS, GE-IS, UNII-OWD43055HV, 2-Propanediol”
Synthetic
Ingredient Facts
Isostearyl glyceryl ether
AKA: Monoisostearyl glyceryl ether, GE-IS cpd, RefChem:149991, Penetol GE-IS, GE-IS, UNII-OWD43055HV, 2-Propanediol
Synthetic · Emollient · EWG: 4
Plant-Derived
Emollient
Skin Conditioner
Plant Oil
Synthetic
Clean
A naturally-derived moisturizer that softens and conditions skin, helping it feel smooth and hydrated throughout the day.
Formula
C21H44O3
Mol. Weight
344.60
CAS #
78145-84-3
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks in moisture
Traditional Use
A synthetic emollient derived from isostearyl alcohol and glycerin, developed in the late 20th century. Used in cosmetics to provide hydration, slip, and skin conditioning without excessive greasiness.
Skin Types
●all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
Isostearyl Glyceryl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isostearyl Glyceryl Ether
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.
Fujii MY, Asakawa Y, Fukami T
International journal of pharmaceutics, 2020
Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability-a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal D
Sano T, Okada A, Kawasaki K, Kume T, Fukui M et al.
AAPS PharmSciTech, 2022
Self-Assembled Structure of α-Isostearyl Glyceryl Ether Affects Skin Permeability-a Lamellar with 70-nm Spaces and L3 Phase Enhanced the Transdermal D
Sano T, Okada A, Kawasaki K, Kume T, Fukui M et al.
AAPS PharmSciTech, 2022
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR