Lactoglobulin
AKA “9045-23-2, Lactoglobulins, beta-, .beta.-, RefChem:798376, EINECS 232-928-9, 232-928-9, (2R, 4R)-2-methyl-4-[(4-octylphenyl)methoxy]pyrrolidine;hydrochloride, |A-Lactoglobulin, C20H34ClNO, 2-methyl-4-((4-octylbenzyl)oxy)pyrrolidine hydrochloride
Skin Conditioning
Ingredient Facts
Lactoglobulin
AKA: 9045-23-2, Lactoglobulins, Beta-, .beta.-, RefChem:798376, EINECS 232-928-9, 232-928-9, (2R, 4R)-2-methyl-4-[(4-octylphenyl)methoxy]pyrrolidine;hydrochloride, |A-Lactoglobulin, C20H34ClNO, 2-methyl-4-((4-octylbenzyl)oxy)pyrrolidine hydrochloride
Skin Conditioning · Antistatic · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
Lactoglobulins, .beta.-
Formula
C20H34ClNO
Mol. Weight
339.90
CAS #
9045-23-2
Form
Powder
State
Powder; [Sigma-Aldrich MSDS]
See origin →
Functions
Antistatic
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Lactoglobulin is a whey protein first identified in the late 19th century. Used in 20th-century cosmetics for its protein-conditioning and skin-barrier supporting properties.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Beta-Carotene.
, 2006
Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cy
Adachi H, Irie T, Uekama K, Manako T, Yano T et al.
The Journal of pharmacy and pharmacology, 1992
Inhibitory effect of prostaglandin E1 on laurate-induced peripheral vascular occlusive sequelae in rabbits: optimized topical formulation with beta-cy
Adachi H, Irie T, Uekama K, Manako T, Yano T et al.
The Journal of pharmacy and pharmacology, 1992
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Caryophyllene
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Glucan Hydroxypropyltrimonium Chloride
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Glucan Palmitate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Sitosteryl Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Hydrolyzed Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
Lactoglobulin
European Commission
EU Cosmetic Ingredient Database (CosIng)
Oxidized Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
Sodium Carboxymethyl Beta-Glucan
European Commission
EU Cosmetic Ingredient Database (CosIng)
8'-Apo-Beta-Carotenal
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Beta-Caryophyllene
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Hydrolyzed Beta-Glucan
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Lactoglobulin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Sodium Carboxymethyl Beta-Glucan
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Mannitol Is a Good Anticaking Agent for Spray-Dried Hydroxypropyl-Beta-Cyclodextrin Microcapsules.
Kou X, Zhang X, Cheng Y, Yu M, Meng Q et al.
Molecules (Basel, Switzerland), 2023
Safety of alpha-arbutin and beta-arbutin in cosmetic products
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
Human beta-defensin-2.
Schröder JM, Harder J
The international journal of biochemistry & cell biology, 1999
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR