Lactulose
AKA “D-Lactulose, 4618-18-2, Bifiteral, Cephulac, Chronulac, Constilac, Lactulosa, Acilac, Cholac
Humectant
Ingredient Facts
Lactulose
AKA: D-Lactulose, 4618-18-2, Bifiteral, Cephulac, Chronulac, Constilac, Lactulosa, Acilac, Cholac
Humectant · Humectant · EWG: 4
Synthetic
Humectant
Skin Conditioner
Not Clean
D-Fructose, 4-0-.beta.-D-galactopyranosyl-
Solubility Soluble in cold water, hot water. Solubility in water: 76.4% @ 30 deg. C
Formula
C12H22O11
Mol. Weight
342.30
CAS #
4618-18-2
Form
Powder
State
Solid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
Lactulose is a synthetic disaccharide developed in the 20th century. Used in cosmetics as a humectant and prebiotic ingredient believed to support skin microbiome health.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR