Lauroyl Arginine
AKA “N-Lauroyl-L-arginine, N2-(1-Oxododecyl)-L-arginine, EINECS 255-851-2, UNII-65091WP61D, AMISAFE AL 01, AMISAFE AL-01, 65091WP61D, ARGININE, N2-LAUROYL-, DTXSID10195279”
Skin Conditioning
Ingredient Facts
Lauroyl arginine
AKA: N-Lauroyl-L-arginine, N2-(1-Oxododecyl)-L-arginine, EINECS 255-851-2, UNII-65091WP61D, AMISAFE AL 01, AMISAFE AL-01, 65091WP61D, N2-LAUROYL-, DTXSID10195279
Skin Conditioning · Hair Conditioning · EWG: 1
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Clean
The panel concluded that the 115 amino acid alkyl amides listed below are safe in the present practices of use and concentration in cosmetics, when formulated to be non-irritating...Lauroyl Arginine
Formula
C18H36N4O3
Mol. Weight
356.50
CAS #
42492-22-8
Form
Powder
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Synthetic derivative combining lauric acid with the amino acid arginine, developed in modern cosmetic chemistry to provide conditioning and antimicrobial properties in skincare and haircare products.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
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Assessment of primary eye and skin irritants by in vitro cytotoxicity and phototoxicity models: an in vitro approach of new arginine-based surfactant-
Benavides T, Mitjans M, Martínez V, Clapés P, Infante MR et al.
Toxicology, 2004
Restructuring of Lipid Membranes by an Arginine-Capped Peptide Bolaamphiphile.
Castelletto V, Barnes RH, Karatzas KA, Edwards-Gayle CJC, Greco F et al.
Langmuir : the ACS journal of surfaces and colloids, 2019
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Altered Arginine Metabolism Affects Proliferation and Radiosensitivity of Keloids.
Li W, Li X, Zhang Y, Zhu B, Xu X et al.
Experimental dermatology, 2025
Antimicrobial Nanoparticles Composed of Zein and Arginine-Phenylalanine-Based Surfactants for Wound Related Infections: Antioxidant and Skin-Related A
Sousa FFO, Hafidi Z, García MT, Moran MDC, Vazquez S et al.
Antibiotics (Basel, Switzerland), 2024
Effects of growth factors and L-arginine on ischemic skin flaps in rats.
Walls CM, Gregory CR, Beck LS, Cooke JP, Griffey SM et al.
Veterinary surgery : VS, 1995
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR