Linoleic Acid
AKA “60-33-3, Linolic acid, (9Z, 12Z)-octadeca-9, 12-dienoic acid, Telfairic acid, cis, cis-Linoleic acid, 9, 12-Linoleic acid, Unifac 6550, Emersol 315, alpha-Linoleic acid
Synthetic
Ingredient Facts
Linoleic acid
AKA: 60-33-3, Linolic acid, (9Z, 12Z)-octadeca-9, 12-dienoic acid, Telfairic acid, Cis, Cis-Linoleic acid, 9, 12-Linoleic acid, Unifac 6550, Emersol 315, Alpha-Linoleic acid
Synthetic · Buffering · EWG: 1
Synthetic
Skin Conditioner
Plant Oil
Synthetic
Clean
Linoleic acid is a doubly unsaturated fatty acid, also known as an omega-6 fatty acid, occurring widely in plant glycosides. In this particular polyunsaturated fatty acid (PUFA), the first double bond is located between the sixth and seventh carbon atom from the methyl end of the fatty acid (n-6). Linoleic acid is an essential fatty acid in human nutrition because it cannot be synthesized by humans. It is used in the biosynthesis of prostaglandins (via arachidonic acid) and cell membranes. (From Stedman, 26th ed).
Solubility Insoluble (NTP, 1992)
Formula
C18H32O2
Mol. Weight
280.40
CAS #
60-33-3
Form
Liquid
State
Linoleic acid is a colorless to straw colored liquid. A polyunsaturated fatty acid essential to human diet.
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Buffering
Reduces Static
Removes Impurities
Conditions Hair
Conditions Skin
Traditional Use
This is the CAS number for glycerin (Vegetin). Glycerin has been used since antiquity in skincare preparations and was historically extracted from animal fats and plant oils for its humectant properties.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Dilinoleic Acid/Butanediol Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isomerized Linoleic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
PEG-8 Dimethicone/Dimer Dilinoleic Acid Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
Trilinoleic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dilinoleic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Dilinoleic Acid/Butanediol Copolymer
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isomerized Linoleic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Linoleic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Efficacy of an emollient containing diethylene glycol/dilinoleic acid copolymer for the treatment of dry skin and pruritus in patients with senile xer
Izumi R, Negi O, Suzuki T, Tominaga M, Kamo A et al.
Journal of cosmetic dermatology, 2017
Linoleic Acid Induced Changes in SZ95 Sebocytes-Compariso...
Dóra Kovács, Emanuela Camera, Szilárd Póliska, Alessia Cavallo, Miriam Maiellaro, Katalin Dull + 4 more
Nutrients, 2023
Effect of a combination of medium chain triglycerides, linoleic acid, soy lecithin and vitamins A and E on wound healing in rats.
Magalhães MS, Fechine FV, Macedo RN, Monteiro DL, Oliveira CC et al.
Acta cirurgica brasileira, 2008
Fatty acid composition and productive traits of broiler fed diets containing conjugated linoleic acid.
Sirri F, Tallarico N, Meluzzi A, Franchini A
Poultry science, 2003
The Role of Linoleic Acid in Skin and Hair Health: A Review.
Xi Wang, Yan Jia, Huaming He
International journal of molecular sciences, 2024
The Role of Linoleic Acid in Skin and Hair Health: A Review.
Xi Wang, Yan Jia, Huaming He
International journal of molecular sciences, 2024
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR