Lysine
AKA “L-lysine, lysine acid, h-Lys-oh, (S)-Lysine, Aminutrin, alpha-Lysine, (S)-2, 6-Diaminohexanoic acid”
Synthetic
Ingredient Facts
Lysine
AKA: L-lysine, Lysine acid, H-Lys-oh, (S)-Lysine, Aminutrin, Alpha-Lysine, (S)-2, 6-Diaminohexanoic acid
Synthetic · Antistatic · EWG: 4
Synthetic
Skin Conditioner
Amino Acid
Synthetic
Clean
An amino acid that helps smooth and soften hair while reducing static and frizz for a sleeker appearance.
Effective at 0.35%
Solubility 1000000
Formula
C6H14N2O2
Mol. Weight
146.19
CAS #
56-87-1
Form
Powder
State
Liquid
See origin →
Functions
Antistatic
Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Reduces Static
Conditions Hair
Softens & Smooths
Reduces Flyaways
Detangles Hair
Traditional Use
An amino acid discovered in the late 19th century. While primarily known for internal immune support, L-lysine has been studied since the 1980s for skincare applications, particularly for supporting skin barrier function and reducing inflammation.
Skin Types
●all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
all-shades-safe
Concentration Guide
2e-05%
0.7%
0%100%
Effective Range
CIR reported use: 0.0009-0.001 | 0.00002-0.7 | 0.00003-0.6
Regulatory Agencies
Lauroyl Lysine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Lysine HCl
European Commission
EU Cosmetic Ingredient Database (CosIng)
Safety and efficacy of l-lysine monohydrochloride and concentrated liquid l-lysine (base) produced by fermentation with Corynebacterium glutamicum KCC
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H et al.
EFSA journal. European Food Safety Authority, 2020
Lauroyl Lysine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Lysine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Sodium Dilauramidoglutamide Lysine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Novel design of pyrrolidonecarboxylic acid and sodium dilauramidoglutamide lysine complex for targeted drug delivery to human stratum corneum.
Fujii MY, Manabe H, Ogura T
International journal of pharmaceutics, 2025
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR