Magnesium Acetate
AKA “142-72-3, Magnesium diacetate, ACETIC ACID, MAGNESIUM SALT, Mg Acetate, Magnesium di(acetate), Acetic acid magnesium salt, Mg(II) acetate, Magnesium acetate anhydrous, Acetic acid, magnesium salt (2:1)”
Ingredient
Ingredient Facts
Magnesium acetate
AKA: 142-72-3, Magnesium diacetate, ACETIC ACID, MAGNESIUM SALT, Mg Acetate, Magnesium di(acetate), Acetic acid magnesium salt, Mg(II) acetate, Magnesium acetate anhydrous, Acetic acid, Magnesium salt (2:1)
Ingredient · Buffering · EWG: 1
Synthetic
Clean
Magnesium Acetate is the acetate salt form of magnesium. Magnesium is a divalent cation essential for a number of biochemical processes involved in nerve signaling, bone mineralization and muscle contractions. About 350 enzymes involved in glycolysis and the Krebs cycle, formation of cyclic-AMP and ATP, cellular signal transduction and protein and nucleic acid synthesis are dependent on magnesium.
Formula
C4H6MgO4
Mol. Weight
142.39
CAS #
142-72-3
Form
Powder
State
Liquid; Pellets or Large Crystals
See origin →
Functions
Buffering
Anti-Inflammatory
Fights Acne
Antioxidant
Maintains optimal pH
Traditional Use
A salt form of magnesium developed for cosmetic and pharmaceutical use in the 20th century; used primarily as a preservative and antimicrobial agent in skincare formulations.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics.
Burnett CL, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Sodium Dehydroacetate and Dehydroacetic Acid.
Cherian P, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2024
Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Sodium Dehydroacetate and Dehydroacetic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Acetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Beta-Alanine Diacetic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
dehydroacetic acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Magnesium Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Evaluation of calcium magnesium acetate and road salt for contact hypersensitivity potential and dermal irritancy in humans.
Cushman JR, Duff VA, Buteau GH, Aust LB, Caldwell N et al.
Contact dermatitis, 1991
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic acid and the skin: a review of vinegar in dermatology.
Elhage KG, St Claire K, Daveluy S
International journal of dermatology, 2022
Acetic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
dehydroacetic acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Magnesium Acetate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Potential application of novel liquid crystal nanoparticles of isostearyl glyceryl ether for transdermal delivery of 4-biphenyl acetic acid.
Fujii MY, Asakawa Y, Fukami T
International journal of pharmaceutics, 2020
Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice.
Fukami H, Tachimoto H, Kishi M, Kaga T, Waki H et al.
Journal of lipid research, 2010
Trichloroacetic acid
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR