Maleic Acid
AKA “110-16-7, cis-butenedioic acid, Toxilic acid, (2Z)-but-2-enedioic acid, Maleinic acid, Malenic acid, (Z)-Butenedioic acid, cis-1, 2-Ethylenedicarboxylic acid, 2-Butenedioic acid (Z)-
Acid
Ingredient Facts
Maleic acid
AKA: 110-16-7, Cis-butenedioic acid, Toxilic acid, (2Z)-but-2-enedioic acid, Maleinic acid, Malenic acid, (Z)-Butenedioic acid, Cis-1, 2-Ethylenedicarboxylic acid, 2-Butenedioic acid (Z)-
Acid · Buffering · EWG: 4
Synthetic
Safety Concern
Acid
Not Clean
Maleic acid is an industrial raw material for the production of glyoxylic acid by ozonolysis. Maleic acid is an organic compound which is a dicarboxylic acid (molecule with two carboxyl groups). The molecule consists of an ethylene group flanked by two carboxylic acid groups. Maleic acid is the cis isomer of butenedioic acid, whereas fumaric acid is the trans isomer. The cis isomer is the less stable one of the two; the difference in heat of combustion is 22.7 kJ/mol. The physical properties of maleic acid are very different from that of fumaric acid. Maleic acid is soluble in water whereas fumaric acid is not and the melting point of maleic acid (130 - 131 degree centigrade) is also much lower than that of fumaric acid (287 degree centigrade). Both properties of maleic acid can be explained on account of the intramolecular hydrogen bonding that takes place at the expense of intermolecular interactions. Maleic acid is converted into maleic anhydride by dehydration, to malic acid by hyd
Solubility greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
Formula
C4H4O4
Mol. Weight
116.07
CAS #
110-16-7
Form
Liquid
State
Maleic acid is a colorless crystalline solid having a faint odor. It is combustible though it may take some effort to ignite. It is soluble in water. It is used to make other chemicals and for dyeing
See origin →
Functions
Buffering
Stabilizes pH
Brightens Skin
Traditional Use
A synthetic organic acid discovered in the 19th century, derived from maleic anhydride. Used in modern skincare as a chemical exfoliant and pH buffer, though no traditional cosmetic use exists.
Skin Types
all-skin-types
Best For
Uneven Texture
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR