Methoxyisopropyl Acetate
AKA “Propylene glycol methyl ether acetate, PGMEA cpd, RefChem:433493, 1-Methoxy-2-propyl acetate, 108-65-6, 1-methoxypropan-2-yl acetate, Propylene glycol monomethyl ether acetate, 2-Acetoxy-1-methoxypropane, 1-Methoxy-2-acetoxypropane
Ingredient
Ingredient Facts
Methoxyisopropyl acetate
AKA: Propylene glycol methyl ether acetate, PGMEA cpd, RefChem:433493, 1-Methoxy-2-propyl acetate, 108-65-6, 1-methoxypropan-2-yl acetate, Propylene glycol monomethyl ether acetate, 2-Acetoxy-1-methoxypropane, 1-Methoxy-2-acetoxypropane
Ingredient · Solvent · EWG: 4
Synthetic
Solvent
Not Clean
2-methoxy-1-methylethyl acetate
Solubility In water, 1.98X10+5 mg/L at 25 °C
Formula
C6H12O3
Mol. Weight
132.16
CAS #
108-65-6
Form
Liquid
State
Propylene glycol methyl ether acetate is a colorless liquid with a sweet ether-like odor. (USCG, 1999)
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
A modern synthetic solvent created for cosmetic formulations. Used in skincare and color cosmetics to improve texture, evaporation, and product performance.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR