Methyl Cyclodextrin
AKA “SCHEMBL29349782
Ingredient
Ingredient Facts
Methyl cyclodextrin
AKA: SCHEMBL29349782
Ingredient · Chelating · EWG: 1
Synthetic
Chelating Agent
Clean
See also: beta-Cyclodextrin, methyl ethers (annotation moved to); Methyl Cyclodextrin (annotation moved to).
Formula
C37H62O30
Mol. Weight
986.90
CAS #
128446-36-6
Form
Powder
See origin →
Functions
Chelating
Grabs onto metal ions in water that would destabilize the formula. Keeps your product from going bad or changing color.
Removes Metal Ions
Anti-Aging Benefits
Antioxidant Protection
Reduces Inflammation
Binds metal ions
Traditional Use
A synthetic derivative of cyclodextrin, developed in the late 20th century. Designed to improve the solubility and bioavailability of active ingredients in cosmetic formulations.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
Dermal absorption: 2%. Source: CIR Safety Assessment (CIR Seq 680).
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR