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Methylpropanediol
AKA “2-Methyl-1, 3-propanediol, 2163-42-0, 1, 3-Propanediol, 2-methyl-, N8F53B3R4R, .BETA.-HYDROXYISOBUTANOL, HSDB 7267, MP Diol, RefChem:818687, 3Propanediol, 2methyl”
Synthetic
Ingredient Facts
Methylpropanediol
AKA: 2-Methyl-1, 3-propanediol, 2163-42-0, 1, 3-Propanediol, 2-methyl-, N8F53B3R4R, .BETA.-HYDROXYISOBUTANOL, HSDB 7267, MP Diol, RefChem:818687, 3Propanediol, 2methyl
Synthetic · Humectant · EWG: 1
Synthetic
Humectant
Solvent
Synthetic
Clean
See also: Glycerin; methylpropanediol (component of).
Solubility In water, greater than or equal to 3000 mg/L at 25 °C
Formula
C4H10O2
Mol. Weight
90.12
CAS #
2163-42-0
Form
Liquid
State
Liquid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Dissolves other ingredients
Traditional Use
Insufficient ingredient name provided; cannot identify or describe traditional use.
Skin Types
●all-skin-types
Best For
General
EWG
1
CIR
Insufficient
Pregnancy
—
CIR Safety Findings
all-shades-safe
Moderate Irritant
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Refreshing Water Mist
COOLA
 →
holi (sun) spf 50 dewy tinted skin drops
Agent Nateur
 →
the body duo
Agent Nateur
 →
lactic acid cleanser duo
Agent Nateur
 →
the vitamin c and hyaluronic brightening duo
Agent Nateur
 →
holi (soleil) firming & plumping mineral spf 50 sunscreen
Agent Nateur
 →
the after (glow) set: ruby
Agent Nateur
 →
the after (glow) set: rose quartz
Agent Nateur
 →
Sunlit Essentials Set
Indie Lee
 →
Tulip Dew Sunscreen Serum
Bloom Effects
 →
Tulipscreen™ Hydrating Lip Oil
Bloom Effects
 →
Radiance Reset
Bloom Effects
 →
Everyday Radiance Essentials
Bloom Effects
 →
Daily SPF 50 Primer
Indie Lee
 →
Supernatural Radiance Serum Broad Spectrum SPF 30 Sunscreen
RMS Beauty
 →
SunCoverup Super Tint Broad Spectrum SPF 50 Sunscreen
RMS Beauty
 →
The ILIA Look
ILIA Beauty
 →
Super Serum Skin Tint SPF 40
ILIA Beauty
 →
Super Serum Skin Tint SPF 30
ILIA Beauty
 →
SunCoverup Super Tint SPF 50
RMS Beauty
 →
Final Report on the Safety Assessment of 2-Methyl-5-Hydroxyethylaminophenol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Aminomethylpropanol and Aminomethylpropanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
2-Methyl-5-Hydroxyethylaminophenol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
2-Methyl-1-Phenyl-2-Propanol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
2-Methyl-5-Hydroxyethylaminophenol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methylpropanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
2-Methyl-m-phenylenediamine
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
Progress in 1,3-propanediol biosynthesis.
Li B, Gao W, Pan Y, Yao Y, Liu G
Frontiers in bioengineering and biotechnology, 2024
→
Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function.
Pinto JR, Monteiro E Silva SA, Leonardi GR
International journal of cosmetic science, 2024
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR