Methylsulfonylmethane (MSM)
AKA “MSM
Ingredient
Ingredient Facts
Methylsulfonylmethane (MSM)
Ingredient · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Medicated Active
Not Clean
Methylsulfonylmethane (MSM) is a cosmetic ingredient.
Formula
C2H6O2S
Mol. Weight
94.14
CAS #
67-71-0
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Dissolves Ingredients
Controls Viscosity
Wound Healing
Antioxidant Protection
Reduces Inflammation
Traditional Use
Developed in the 1980s as a dietary supplement, MSM was researched for joint health and connective tissue support. It was later introduced to skincare based on studies suggesting it supports collagen production and skin elasticity.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR