MIBK
AKA “4-Methyl-2-pentanone, METHYL ISOBUTYL KETONE, 4-Methylpentan-2-one, Isopropylacetone, Isobutyl methyl ketone, Hexone, 2-Pentanone, 2-Methyl-4-pentanone
Synthetic
Ingredient Facts
MIBK
AKA: 4-Methyl-2-pentanone, METHYL ISOBUTYL KETONE, 4-Methylpentan-2-one, Isopropylacetone, Isobutyl methyl ketone, Hexone, 2-Pentanone, 2-Methyl-4-pentanone
Synthetic · Denaturant · EWG: 4
Synthetic
Fragrance
Solvent
Synthetic
Clean
A lightweight solvent that helps dissolve and blend formula ingredients together, while also carrying subtle fragrance notes through the product.
Solubility 1 to 5 mg/mL at 70 °F (NTP, 1992)
Formula
C6H12O
Mol. Weight
100.16
CAS #
108-10-1
Form
Liquid
State
Methyl isobutyl ketone appears as a clear colorless liquid with a pleasant odor. Flash point 73 °F. Less dense than water. Vapors heavier than air.
See origin →
Functions
Denaturant
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Makes Alcohol Undrinkable
Adds Fragrance
Dissolves Ingredients
Locks In Moisture
Adds pleasant scent
Dissolves other ingredients
Traditional Use
Methyl isobutyl ketone, a synthetic solvent developed in the early 20th century. Used in cosmetics manufacturing and historically in nail products, largely phased out due to toxicity concerns.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
No
EWG
4
CIR
Unsafe
Pregnancy
No
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USArestricted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR