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Mixed Cresols
AKA “Cresol mix, methylphenols, o-cresol, m-cresol, p-cresol”
Ingredient
Ingredient Facts
Mixed cresols
AKA: Cresol mix, Methylphenols, O-cresol, M-cresol, P-cresol
Ingredient · Antimicrobial · EWG: 3
Synthetic
Preservative
Fragrance
Not Clean
Phenol, methyl-
Formula
C7H8O
Mol. Weight
108.14
CAS #
1319-77-3
Form
Liquid
See origin →
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Fights Bacteria
Traditional Use
Phenolic compounds first isolated from coal tar in the 19th century. Adopted in early cosmetics and pharmaceuticals as antimicrobial preservatives, though largely phased out in modern skincare due to safety concerns.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
EWG
3
CIR
Insufficient data
Pregnancy
No
CIR Safety Findings
all-shades-safe
Potential Sensitizer
Regulatory Status
USAunder review
CANADA✔ permitted
Regulatory Agencies
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
→
Final report on the safety assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol, a
International journal of toxicology, 2004
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Final report on the safety assessment of sodium p-chloro-m-cresol, p-chloro-m-cresol, chlorothymol, mixed cresols, m-cresol, o-cresol, p-cresol, isopr
Andersen A
International journal of toxicology, 2006
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Final report on the safety assessment of sodium p-chloro-m-cresol, p-chloro-m-cresol, chlorothymol, mixed cresols, m-cresol, o-cresol, p-cresol, isopr
Andersen A
International journal of toxicology, 2006
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Final report on the safety assessment of sodium p-chloro-m-cresol, p-chloro-m-cresol, chlorothymol, mixed cresols, m-cresol, o-cresol, p-cresol, isopr
Andersen A
International journal of toxicology, 2006
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Final report on the safety assessment of sodium p-chloro-m-cresol, p-chloro-m-cresol, chlorothymol, mixed cresols, m-cresol, o-cresol, p-cresol, isopr
Andersen A
International journal of toxicology, 2006
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Final Report Amended Report: Safety Assessment of 6-Amino-m-Cresol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report Amended Report: Safety Assessment of 6-Amino-o-Cresol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of 6-Amino-m-Cresol, 6-Amino-o-Cresol, 4-Amino-m-Cresol, 5-Amino-4-Chloro-o-Cresol, 5-Amino-6-Chloro-o-Cresol and 4-Chloro-2-Aminophenol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of p-Chloro-m-Cresol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report on the Safety Assessment of Sodium p-Chloro-m-Cresol, p-Chloro-m-Cresol, Chlorothymol, Mixed Cresols, m-Cresol, o-Cresol, p-Cresol, Isopropyl Cresols, Thymol, o-Cymen-5-ol and Carvacrol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report: Amended Safety Assessment of 4-Amino-m-Cresol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report: Amended Safety Assessment of 5-Amino-4-Chloro-o-Cresol and 5-Amino-4-Chloro-o-Cresol HCl as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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Final Report: Amended Safety Assessment of 5-Amino-6-Chloro-o-Cresol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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4-Amino-m-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
5-Amino-4-Chloro-o-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
5-Amino-4-Chloro-o-Cresol HCl
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
5-Amino-6-Chloro-o-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
6-Amino-m-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
m-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Mixed Cresols
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
o-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
p-Chloro-m-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
p-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Sodium p-Chloro-m-Cresol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
4-Amino-m-Cresol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
5-Amino-6-Chloro-o-Cresol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
m-Cresol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
o-Cresol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
p-Chloro-m-cresol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
p-Cresol and mixtures thereof
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
Urinary p-cresol in autism spectrum disorder.
Persico AM, Napolioni V
Neurotoxicology and teratology, 2013
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Allergenicity evaluation of p-chloro-m-cresol and p-chloro-m-xylenol by non-radioactive murine local lymph-node assay and multiple-dose guinea pig max
Yamano T, Shimizu M, Noda T
Toxicology, 2003
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Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR