Myristoyl Hexapeptide-12
AKA “RefChem:819745, COLLASYN 614 VG, ZWF521YI75, MYR-VAL-GLY-VAL-ALA-PRO-GLY, (val-gly-val-ala-pro-gly)-myristoyl hexapeptide-12, Q27295923, GLYCINE, N-(1-OXOTETRADECYL)-L-VALYLGLYCYL-L-VALYL-L-ALANYL-L-PROLYL-
Skin Conditioning
Ingredient Facts
Myristoyl hexapeptide-12
AKA: RefChem:819745, COLLASYN 614 VG, ZWF521YI75, MYR-VAL-GLY-VAL-ALA-PRO-GLY, (val-gly-val-ala-pro-gly)-myristoyl hexapeptide-12, Q27295923, GLYCINE, N-(1-OXOTETRADECYL)-L-VALYLGLYCYL-L-VALYL-L-ALANYL-L-PROLYL-
Skin Conditioning · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Amino Acid
Not Clean
Myristoyl Hexapeptide-12 is a reaction product of Myristic Acid and Hexapeptide-12
Formula
C36H64N6O8
Mol. Weight
708.90
CAS #
-
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Reduces fine lines
Traditional Use
Modern synthetic peptide conjugate derived from myristic acid, developed in the late 20th century as a cosmetic active ingredient intended to provide skin-conditioning effects; no traditional use.
Skin Types
all-skin-types
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Capryloyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Callus Culture
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Callus Culture Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Callus Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Flower/Leaf/Stem Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Leaf Cell Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Leaf Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Phytoplacenta Conditioned Media
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Polypeptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Pulp
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Seedcoat Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Max (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Flour
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Germ Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Hull
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Peptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Seed
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Seed Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
Glycine Soja (Soybean) Sterols
European Commission
EU Cosmetic Ingredient Database (CosIng)
Myristoyl Hexapeptide-12
European Commission
EU Cosmetic Ingredient Database (CosIng)
Palmitoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Undecylenoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Capryloyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soy) Peptides
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Flour
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Germ Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Oil Unsaponifiables
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Phytoplacenta Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Seed
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Sprout Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja (Soybean) Sterols
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Glycine Soja Soybean Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Palmitoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Undecylenoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Capryloyl glycine: A polyfunctional cosmetic ingredient and potential skin sensitizer.
Mangodt EA, Dendooven E, De Fré C, Lambert J, Aerts O
Contact dermatitis, 2019
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR