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Myristyl Salicylate
AKA “Myristyl 2-hydroxybenzoate, 1-Tetradecanol, salicylate, UNII-B7N453V88S, 2-Hydroxybenzoic acid, tetradecyl ester, Benzoic acid”
Synthetic
Ingredient Facts
Myristyl salicylate
AKA: Myristyl 2-hydroxybenzoate, 1-Tetradecanol, UNII-B7N453V88S, 2-Hydroxybenzoic acid, Tetradecyl ester, Benzoic acid
Synthetic · Emollient · EWG: 4
Synthetic
Emollient
Occlusive
Skin Conditioner
Chemical Exfoliant
Synthetic
Clean
A lightweight conditioning agent that helps soften and smooth skin, leaving it feeling supple and hydrated.
Formula
C21H34O3
Mol. Weight
334.50
CAS #
19666-17-2
Form
Oil
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Locks in moisture
Traditional Use
A synthetic ester combining myristic acid with salicylic acid, developed in the 20th century. Created as a gentle exfoliating agent that provides chemical exfoliation properties similar to beta hydroxy acids.
Skin Types
●all-skin-types
Best For
Uneven Texture
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe
Pregnancy
Caution
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Iso
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report: Safety Assessment of Benzyl Salicylate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
→
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Amyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Benzyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
C12-15 Alkyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Calcium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Ethylhexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Hexyldodecyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isocetyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Isodecyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Magnesium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
MEA-Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Methyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Myristyl Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Potassium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
TEA-Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Titanium Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Zinc Salicylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Safety assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicy
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2003
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Amyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Butyloctyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Hexyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Isodecyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Magnesium Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Sodium Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
TEA-Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Tridecyl Salicylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Methyl salicylate
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
GC-MS/MS quantification of benzyl salicylate on skin and hair: A novel chemical simulant for human decontamination studies.
James T, Collins S, Amlôt R, Marczylo T
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics.
Johnson W Jr, Zhu J, Bergfeld WF, Belsito DV, Hill RA et al.
International journal of toxicology, 2025
→
Fragrance material review on hexyl salicylate.
Lapczynski A, Jones L, McGinty D, Bhatia S, Letizia CS et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
→
Addendum to the Scientific Opinion on Hexyl Salicylate SCCS/1658/23 (CAS/EC No. 6259-76-3/228-408-6) - Children exposure 0-3 years old
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Scientific advice – children’s exposure to Methyl salicylate (methyl 2-hydroxybenzoate) - Revision of SCCS/1654/23
Scientific Committee on Consumer Safety (SCCS)
European Commission — SCCS
→
Topical delivery of salicylates.
Yeoh SC, Goh CF
Drug delivery and translational research, 2022
→
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR