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N-Phenyl-p-Phenylenediamine
AKA “4-Aminodiphenylamine, 101-54-2, P-AMINODIPHENYLAMINE, p-Anilinoaniline, Variamine Blue RT, Azosalt R, Luxan Black R, p-Semidine, N-Phenyl-1, 4-phenylenediamine”
Ingredient
Ingredient Facts
N-Phenyl-p-Phenylenediamine
AKA: 4-Aminodiphenylamine, 101-54-2, P-AMINODIPHENYLAMINE, P-Anilinoaniline, Variamine Blue RT, Azosalt R, Luxan Black R, P-Semidine, N-Phenyl-1, 4-phenylenediamine
Ingredient · Hair Dyeing · EWG: 10
Synthetic
Not Clean
N-(4-Aminophenyl)aniline (CI 76085)
Solubility less than 1 mg/mL at 66 °F (NTP, 1992)
Formula
C12H12N2
Mol. Weight
184.24
CAS #
101-54-2
Form
Liquid
State
N-phenyl-p-phenylenediamine appears as odorless purple-black solid or flake or dark purple chips. (NTP, 1992)
See origin →
Functions
Hair Dyeing
Boosts Collagen
Fights Acne
Colors hair
Traditional Use
Synthetic organic compound developed in the 20th century as a permanent hair dye component. Used to create dark hair colors by oxidative coupling with other dye intermediates.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ PPD (Hair Dye)
EWG
10
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU✔ permitted
JAPAN✔ permitted
CANADA✔ permitted
🧂Conflict of interest.
Final Report on the Safety Assessment of N-Phenyl-p-Phenylenediamine, N-Phenyl-p-Phenylenediamine Hydrochloride, and N-Phenyl-p-Phenylenediamine Sulfate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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N-Phenyl-p-Phenylenediamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
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N-Phenyl-p-Phenylenediamine HCl
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
N-Phenyl-p-Phenylenediamine Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
N-Phenyl-p-Phenylenediamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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N-Phenyl-p-Phenylenediamine Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Dual functionalities of 4-aminodiphenylamine in enzymatic assay and mediated biosensor construction.
Groom CA, Luong JH, Thatipalmala R
Analytical biochemistry, 1995
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Studies on the skin uptake and efflux kinetics of N-phenyl-p-phenylenediamine: an aromatic amine intermediate.
Khanna SK, Tewari P, Joshi A, Singh GB
International journal of cosmetic science, 1987
→
Verified Jun 2026 · 🧪 = conflict
Data: PubChem · CosIng · EWG · CIR