N-Phenyl-p-Phenylenediamine Hydrochloride
AKA “4-Aminodiphenylamine hydrochloride, 1, 4-Benzenediamine, N-phenyl-, monohydrochloride, Eucanine Grey B, Zoba Grey BR, Fourrine Grey B, p-Aminodiphenylamine HCl, Durafur Grey BN, Fouramine Grey A, Futramine Grey B
Ingredient
Ingredient Facts
N-phenyl-p-phenylenediamine hydrochloride
AKA: 4-Aminodiphenylamine hydrochloride, 1, 4-Benzenediamine, Monohydrochloride, Eucanine Grey B, Zoba Grey BR, Fourrine Grey B, P-Aminodiphenylamine HCl, Durafur Grey BN, Fouramine Grey A, Futramine Grey B
Ingredient · Viscosity Controlling · EWG: 4
Synthetic
Not Clean
On the basis of the data included in this report, the CIR Expert Panel concludes that ... N-Phenyl-p-Phenylenediamine Hydrochloride... safe for use in hair dyes at concentrations up to 1.7% (as the free base).
Formula
C12H13ClN2
Mol. Weight
220.70
Form
Liquid
See origin →
Functions
Viscosity Controlling
Boosts Collagen
Fights Acne
Supports collagen production
Helps reduce acne
Causing bacteria
Contributes to skin healing
Traditional Use
Salt derivative of a synthetic hair colorant developed in the 20th century. Used in permanent hair dye formulations as a color-developing agent.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
No
Allergen Warning
⚠️ PPD (Hair Dye)
EWG
4
CIR
Safe as used
Pregnancy
No
CIR Safety Findings
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Final Report on the Safety Assessment of N-Phenyl-p-Phenylenediamine, N-Phenyl-p-Phenylenediamine Hydrochloride, and N-Phenyl-p-Phenylenediamine Sulfate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
N-Phenyl-p-Phenylenediamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
N-Phenyl-p-Phenylenediamine HCl
European Commission
EU Cosmetic Ingredient Database (CosIng)
N-Phenyl-p-Phenylenediamine Sulfate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Safety and efficacy of l-histidine monohydrochloride monohydrate produced using Corynebacterium glutamicum KCCM 80179 for all animal species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, de Lourdes Bastos M, Christensen H et al.
EFSA journal. European Food Safety Authority, 2019
Safety and efficacy of l-lysine monohydrochloride and concentrated liquid l-lysine (base) produced by fermentation with Corynebacterium glutamicum KCC
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Bampidis V, Azimonti G, Bastos ML, Christensen H et al.
EFSA journal. European Food Safety Authority, 2020
N-Phenyl-p-Phenylenediamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
N-Phenyl-p-Phenylenediamine Sulfate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Studies on the skin uptake and efflux kinetics of N-phenyl-p-phenylenediamine: an aromatic amine intermediate.
Khanna SK, Tewari P, Joshi A, Singh GB
International journal of cosmetic science, 1987
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR