Neopentyl Glycol Diisononanoate
AKA “NPDIN, Symmollient L 177205, UNII-3V2Q668IE6, 27841-07-2, 3V2Q668IE6, 1, 3-Bis(3, 5, 5-trimethylhexanoyloxy)-2, 2-dimethylpropane, 2, 2-Dimethylpropane-1, 3-diol di-3, 5-trimethylhexanoate, 3-Propanediol, 2-dimethyl-, bis(3, 5-trimethylhexanoate), Hexanoic acid, 3, 5-trimethyl-, 2-dimethyl-1, 3-propanediyl ester
Emollient
Ingredient Facts
Neopentyl glycol diisononanoate
AKA: NPDIN, Symmollient L 177205, UNII-3V2Q668IE6, 27841-07-2, 3V2Q668IE6, 1, 3-Bis(3, 5, 5-trimethylhexanoyloxy)-2, 2-dimethylpropane, 2, 2-Dimethylpropane-1, 3-diol di-3, 5-trimethylhexanoate, 3-Propanediol, 2-dimethyl-, Bis(3, 5-trimethylhexanoate), Hexanoic acid, 3, 5-trimethyl-, 2-dimethyl-1, 3-propanediyl ester
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Not Clean
Neopentyl Glycol Diisononanoate is a cosmetic ingredient used as skin conditioning - emollient. Also known as NPDIN. Assessed as safe by the CIR.
Formula
C23H44O4
Mol. Weight
384.60
CAS #
-
Form
Liquid
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic branched ester created in the mid-20th century for cosmetics as a light, non-greasy emollient that improves spreadability and skin feel in premium formulations.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR