Nonoxynol-100
AKA “4-Methoxypicolinamide, 90151-10-3, 4-methoxypyridine-2-carboxamide, 4-Methoxy-pyridine-2-carboxylic acid amide, MFCD00955999, 9014-93-1, 4-Methoxypyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide, 4-methoxy-, SCHEMBL2624147, SCHEMBL3355639”
Surfactant
Ingredient Facts
Nonoxynol-100
AKA: 4-Methoxypicolinamide, 90151-10-3, 4-methoxypyridine-2-carboxamide, 4-Methoxy-pyridine-2-carboxylic acid amide, MFCD00955999, 9014-93-1, 4-Methoxypyridine-2-carboxylic acid amide, 2-Pyridinecarboxamide, 4-methoxy-, SCHEMBL2624147, SCHEMBL3355639
Surfactant · Cleansing · EWG: 3
Synthetic
Cleanser
Not Clean
Poly(oxy-1,2-ethanediyl), .alpha.-(dinonylphenyl)-.omega.-hydroxy- (100 mol EO average molar ratio)
Formula
C7H8N2O2
Mol. Weight
152.15
CAS #
9014-93-1
Form
Liquid
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Removes Impurities
Cleansing Surfactant
Traditional Use
A synthetic non-ionic surfactant with high polyethylene glycol content developed in the mid-20th century. Used in cosmetics for solubilization and emulsification of challenging ingredients.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
Final Report on the Safety Assessment of 4-Methoxy-m-Phenylenediamine, 4-Methoxy-m-Phenylenediamine Sulfate, and 4-Methoxy-m-Phenylenediamine-HCI
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Nonoxynol-100
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
4-Methoxy-m-phenylenediamine and its sulfate salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
4-Methoxy-m-phenylenediamine-HCl
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR