Nonoxynol-35
AKA “Nonoxynol 35, POE(35) nonylphenol, Nonylphenol ethoxylate 35
Ingredient
Ingredient Facts
Nonoxynol-35
AKA: Nonoxynol 35, POE(35) nonylphenol, Nonylphenol ethoxylate 35
Ingredient · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Nonoxynol-35 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
Developed in the mid-20th century as a nonionic surfactant and emulsifier. Used in cosmetics and personal care products for its ability to solubilize oils and improve product texture, with no traditional or historical use prior to synthetic polymer development.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR