Nonoxynol-40
AKA “Nonoxynol 40, POE(40) nonylphenol, Nonylphenol ethoxylate 40
Ingredient
Ingredient Facts
Nonoxynol-40
AKA: Nonoxynol 40, POE(40) nonylphenol, Nonylphenol ethoxylate 40
Ingredient · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Nonoxynol-40 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
Nonionic surfactant developed in the mid-20th century for cosmetic formulations. Functions as an emulsifier and solubilizer in modern skincare and personal care products.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR