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Nonoxynol-44
AKA “Nonoxynol 44, POE(44) nonylphenol, Nonylphenol ethoxylate 44”
Ingredient
Ingredient Facts
Nonoxynol-44
AKA: Nonoxynol 44, POE(44) nonylphenol, Nonylphenol ethoxylate 44
Ingredient · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Nonoxynol-44 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
Synthetic surfactant created as part of modernized cosmetic chemistry. Used as an emulsifier in creams and lotions with no traditional antecedent.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR