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Nonoxynol-50
AKA “Nonoxynol 50, POE(50) nonylphenol, Nonylphenol ethoxylate 50”
Ingredient
Ingredient Facts
Nonoxynol-50
AKA: Nonoxynol 50, POE(50) nonylphenol, Nonylphenol ethoxylate 50
Ingredient · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Not Clean
Nonoxynol-50 is a cosmetic ingredient. Assessed as safe by the CIR.
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Traditional Use
Synthetic nonionic surfactant with no traditional use history. Developed for modern cosmetic formulations to enhance product stability and texture.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Moderate Irritant
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: CosIng · EWG · CIR