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Palmitoyl Glycine
AKA “N-Palmitoylglycine, 2441-41-0, 2-(hexadecanoylamino)acetic acid, N-Palmitoyl glycine, N-HEXADECANOYLGLYCINE, Elmiric acid, N-(1-Oxohexadecyl)glycine, N-hexadecanoyl-glycine, M6V3RIU5KI, Glycine, N-(1-oxohexadecyl)-”
Hair Conditioning
Ingredient Facts
Palmitoyl glycine
AKA: N-Palmitoylglycine, 2441-41-0, 2-(hexadecanoylamino)acetic acid, N-Palmitoyl glycine, N-HEXADECANOYLGLYCINE, Elmiric acid, N-(1-Oxohexadecyl)glycine, N-hexadecanoyl-glycine, M6V3RIU5KI, N-(1-oxohexadecyl)-
Hair Conditioning · Cleansing · EWG: 1
Synthetic
Cleanser
Skin Conditioner
Hair Care
Amino Acid
Clean
N-hexadecanoylglycine is an N-acylglycine in which the acyl group is specified as hexadecanoyl (palmitoyl). It has a role as a marine metabolite and a human metabolite. It is a N-acylglycine 16:0 and a fatty amide. It is functionally related to a hexadecanoic acid. It is a conjugate acid of a N-hexadecanoylglycinate.
Formula
C18H35NO3
Mol. Weight
313.50
CAS #
2441-41-0
Form
Liquid
State
Solid
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Anti-Aging
Moisturizing
Improves Elasticity
Removes dirt and impurities
Softens and detangles hair
Traditional Use
A synthetic amino acid conjugate created by combining palmitic acid with glycine. Designed as a modern skincare ingredient to improve hydration and skin barrier function.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
CANADA✔ permitted
Regulatory Agencies
Capryloyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Culture Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Callus Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Flower/Leaf/Stem Juice
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Cell Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Leaf Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Conditioned Media
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Polypeptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Pulp
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Seedcoat Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Max (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Fiber
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Flour
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Germ Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Hull
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Lipids
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Oil Unsaponifiables
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Peptide
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Phytoplacenta Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Protein
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Powder
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seed Water
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Seedcake Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sprout Extract
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Glycine Soja (Soybean) Sterols
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Palmitoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Undecylenoyl Glycine
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Capryloyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soy) Peptides
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Flour
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Germ Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Lipids
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Oil Unsaponifiables
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Phytoplacenta Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Protein
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Seed Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sprout Extract
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja (Soybean) Sterols
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Glycine Soja Soybean Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Palmitoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Undecylenoyl Glycine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Capryloyl glycine: A polyfunctional cosmetic ingredient and potential skin sensitizer.
Mangodt EA, Dendooven E, De Fré C, Lambert J, Aerts O
Contact dermatitis, 2019
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
2-Mercaptonicotinoyl glycine, a new potent melanogenesis ...
Peggy Sextius, Emilie Warrick, Amélie Prévot-Guéguiniat, Guillaume Lereaux, Florence Boirre, Ludwig Baux + 8 more
Pigment cell & melanoma research, 2024
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling.
Sung YY, Kim M, Kim DS, Son E
International journal of molecular sciences, 2025
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR