PEG-45M
AKA “Polyethylene glycol 45M, macrogol 45M, PEG 45M
Humectant
Ingredient Facts
PEG-45M
AKA: Polyethylene glycol 45M, Macrogol 45M, PEG 45M
Humectant · Humectant · EWG: 2
Synthetic
Humectant
Clean
Poly(oxy-1,2-ethanediyl), .alpha.-hydro-.omega.-hydroxy- (45,000 mol EO average molar ratio)
CAS #
25322-68-3
Form
Liquid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
A very high-molecular-weight polyethylene glycol developed for industrial and cosmetic applications. Used as a thickener and texture modifier in modern skincare and cosmetic formulations.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
CANADApermitted
Regulatory Agencies
Verified Jun 2026
Data: CosIng · EWG · CIR