Pentaerythrityl Tetrabenzoate
AKA “
Pentaerythritol tetrabenzoate, Uniplex 552, CCRIS 5971, EINECS 224-079-8, U7L44GIS4O, 2, 2-Bis((benzoyloxy)methyl)-1, 3-propanediol dibenzoate, Pentaerythritol, tetrabenzoate, NSC 166502, BRN 3513249
”
Emollient
🦆
❤️
👻
Ingredient Facts
Pentaerythrityl tetrabenzoate
AKA: Pentaerythritol tetrabenzoate, Uniplex 552, CCRIS 5971, EINECS 224-079-8, U7L44GIS4O, 2, 2-Bis((benzoyloxy)methyl)-1, 3-propanediol dibenzoate, Pentaerythritol, NSC 166502, BRN 3513249
Emollient · Emollient · EWG: 4
WHAT IS IT?
Synthetic
Emollient
Skin Conditioner
Not Clean
Benzoic acid, tetraester with 2,2-bis(hydroxymethyl)-1,3-propanediol
Solubility
less than 1 mg/mL at 66 °F (NTP, 1992)
Formula
C33H28O8
Mol. Weight
552.60
CAS #
4362-18-1
Form
Powder
State
2,2-bis((benzoyloxy)methyl)dibenzoate-1,3-propanediol is a cream-colored solid. (NTP, 1992)
See origin →
WHAT'S IT DO?
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester created by combining pentaerythritol with benzoic acid, developed in the 20th century as a cosmetic film-former and binder.
Skin Types
●
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
IS IT SAFE?
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA
✔ permitted
EU
⚠ restricted
JAPAN
⚠ restricted
CANADA
⚠ restricted
Regulatory Agencies
EWG
CIR
FDA
EU COSING
Health Canada
WHAT'S THE PROOF?
Final Report on the Safety Assessment of Pentaerythritol Rosinate (Amended report IJT 17(S4) 1998)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Pentaerythrityl Tetrabenzoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Allergic contact cheilitis from pentaerythritol rosinate in a lipstick.
Ichihashi K, Soga F, Katoh N, Kishimoto S
Contact dermatitis, 2003
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR