Pentaerythrityl Tetramyristate
AKA “18641-59-3, Pentaerythritol, tetramyristate, UNII-896NIT9V7W, 896NIT9V7W, Myristic acid, tetraester with pentaerythritol, Tetradecanoic acid, 2, 2-bis(((1-oxotetradecyl)oxy)methyl)-1, 3-propanediyl ester, DTXSID00171901, RefChem:171357, DTXCID2094392
Emollient
Ingredient Facts
Pentaerythrityl tetramyristate
AKA: 18641-59-3, Pentaerythritol, UNII-896NIT9V7W, 896NIT9V7W, Myristic acid, Tetraester with pentaerythritol, Tetradecanoic acid, 2, 2-bis(((1-oxotetradecyl)oxy)methyl)-1, 3-propanediyl ester, DTXSID00171901, RefChem:171357, DTXCID2094392
Emollient · Emollient · EWG: 4
Synthetic
Emollient
Skin Conditioner
Not Clean
Tetradecanoic acid, 2,2-bis[(1-oxotetradecyloxy)methyl]-1,3-propanediyl ester
Formula
C61H116O8
Mol. Weight
977.60
CAS #
18641-59-3
Form
Liquid
See origin →
Functions
Emollient
Fills in the tiny cracks between skin cells to make everything feel smooth and soft. The "silky finish" ingredient.
Locks In Moisture
Traditional Use
A synthetic ester developed in the mid-20th century as a cosmetic emollient. Designed to provide lightweight moisture and improve the texture of skincare and makeup formulations without the greasiness of natural oils.
Skin Types
all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Myristic acid reduces skin inflammation and nociception.
Alonso-Castro AJ, Serrano-Vega R, Pérez Gutiérrez S, Isiordia-Espinoza MA, Solorio-Alvarado CR
Journal of food biochemistry, 2022
Final Report of the Amended Safety Assessment of Myristic Acid and its Salts and Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Oleic Acid, Lauric Acid, Palmitic Acid, Myristic Acid, and Stearic Acid
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Pentaerythritol Rosinate (Amended report IJT 17(S4) 1998)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Methyl Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Myristic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
Pentaerythrityl Tetramyristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Myristic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Allergic contact cheilitis from pentaerythritol rosinate in a lipstick.
Ichihashi K, Soga F, Katoh N, Kishimoto S
Contact dermatitis, 2003
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR