Pentapeptide-4
AKA “Lys-Thr-Thr-Lys-Ser, UNII-69B8BD4H9G, Lysylthreonylthreonyllysylserine, 69B8BD4H9G, DTXSID90164180, RefChem:171449, PENTAPEPTIDE-4 [INCI], DTXCID1086671, 149128-48-3
Skin Conditioning
Ingredient Facts
Pentapeptide-4
AKA: Lys-Thr-Thr-Lys-Ser, UNII-69B8BD4H9G, Lysylthreonylthreonyllysylserine, 69B8BD4H9G, DTXSID90164180, RefChem:171449, PENTAPEPTIDE-4 [INCI], DTXCID1086671, 149128-48-3
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Amino Acid
Clean
Pentapeptide-4 is a synthetic peptide containing lysine, serine and threonine
Formula
C23H45N7O9
Mol. Weight
563.60
CAS #
-
Form
Powder
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Reduces fine lines
Traditional Use
A synthetic peptide developed in modern cosmetic research as a potential anti-aging ingredient. Created to stimulate collagen production and improve skin firmness, representing the shift toward peptide-based skincare in the late 20th century.
Skin Types
all-skin-types
Best For
Wrinkles
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR