Phloroglucinol
AKA “Benzene-1, 5-benzenetriol, 5-trihydroxybenzene, Phloroglucin, Phloroglucine, Spasfon-Lyoc, Dilospan S, sym-Trihydroxybenzene
Synthetic
Ingredient Facts
Phloroglucinol
AKA: Benzene-1, 5-benzenetriol, 5-trihydroxybenzene, Phloroglucine, Spasfon-Lyoc, Dilospan S, Sym-Trihydroxybenzene
Synthetic · Antioxidant · EWG: 4
Synthetic
Antioxidant
Soothing
Skin Conditioner
Safety Concern
Synthetic
Clean
A plant-derived compound that helps hair color develop and set, working to enhance dye performance in hair coloring formulas.
Solubility 10.6 mg/mL at 20 °C
Formula
C6H6O3
Mol. Weight
126.11
CAS #
108-73-6
Form
Powder
State
White solid; Discolored by light; [Merck Index] White or cream colored powder; [MSDSonline] Crystallizes in anhydrous or dihydrate form; Sweet tasting crystals; [Ullmann]
See origin →
Functions
Antioxidant
Fights free radicals — the unstable molecules from UV, pollution, and stress that break down collagen and cause premature aging.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Soothing
Calms redness, irritation, and inflammation. Your skin's chill pill — great for sensitive, reactive, or post-procedure skin.
Hair Dyeing
Locks In Moisture
Brightens Skin
Colors Hair
Traditional Use
Isolated from plant sources in the 19th century and used traditionally in European herbalism for skin conditions and inflammatory responses. Later synthesized for use in modern skincare as an antioxidant and skin-soothing agent.
Skin Types
all-skin-types
Best For
Irritation
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USAunder review
EUpermitted
JAPANpermitted
CANADApermitted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR