Phloroglucinol
AKA “108-73-6, Benzene-1, 3, 5-triol, 1, 5-benzenetriol, 5-trihydroxybenzene, Phloroglucin, Phloroglucine, Spasfon-Lyoc, Dilospan S, sym-Trihydroxybenzene
Ingredient
Ingredient Facts
Phloroglucinol
AKA: 108-73-6, Benzene-1, 3, 5-triol, 1, 5-benzenetriol, 5-trihydroxybenzene, Phloroglucine, Spasfon-Lyoc, Dilospan S, Sym-Trihydroxybenzene
Ingredient · Hair Dyeing · EWG: 1
Synthetic
Safety Concern
Clean
On the basis of the available data, the CIR Panel cannot conclude that Phloroglucinol is safe for use in cosmetic products until the appropriate safety data have been obtained and evaluated.
Solubility 10.6 mg/mL at 20 °C
Formula
C6H6O3
Mol. Weight
126.11
CAS #
108-73-6
Form
Powder
State
White solid; Discolored by light; [Merck Index] White or cream colored powder; [MSDSonline] Crystallizes in anhydrous or dihydrate form; Sweet tasting crystals; [Ullmann]
See origin →
Functions
Hair Dyeing
Antioxidant Protection
Locks In Moisture
Brightens Skin
Colors Hair
Traditional Use
Isolated from plant sources in the 19th century and used traditionally in European herbalism for skin conditions and inflammatory responses. Later synthesized for use in modern skincare as an antioxidant and skin-soothing agent.
Skin Types
all-skin-types
Best For
Irritation
Pregnancy & Breastfeeding Safe
Caution
EWG
1
CIR
Safe as used
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR