Poloxamer 108
AKA “CRL-8131, RefChem:1082259, 106392-12-5, 2-methyloxirane;oxirane, TERGITOL(TM)XH(NONIONIC), Pluronic F-68, Pluronic L, 691397-13-4, Pluronic L 122, F-108
Surfactant
Ingredient Facts
Poloxamer 108
AKA: CRL-8131, RefChem:1082259, 106392-12-5, 2-methyloxirane;oxirane, TERGITOL(TM)XH(NONIONIC), Pluronic F-68, Pluronic L, 691397-13-4, Pluronic L 122, F-108
Surfactant · Cleansing · EWG: 4
Synthetic
Cleanser
Emulsifier
Not Clean
Oxirane, methyl-, polymer with oxirane (46;16)
Formula
C5H10O2
Mol. Weight
102.13
CAS #
9003-11-6
Form
Liquid
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Fights Bacteria
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
Traditional Use
Synthesized in the 1950s as part of the poloxamer polymer family. Functions as a surfactant and thickening agent in creams, lotions, and cleansing products.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR