Poloxamer 335
AKA “Pluronic 335, Poloxamer 335, Polyoxypropylene Polyoxyethylene Block Copolymer
Surfactant
Ingredient Facts
Poloxamer 335
AKA: Pluronic 335, Polyoxypropylene Polyoxyethylene Block Copolymer
Surfactant · Cleansing · EWG: 2
Synthetic
Cleanser
Emulsifier
Clean
Oxirane, methyl-, polymer with oxirane (38;54)
CAS #
9003-11-6
Form
Liquid
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Surfactant Cleansing
Surfactant Emulsifying
Anti-Inflammatory
Antimicrobial
Strengthens Barrier
Lifts away dirt and oil
Mixes oil and water
Traditional Use
Developed as a synthetic nonionic surfactant in the mid-20th century for cosmetic applications. Used as an emulsifier and solubilizing agent in modern skincare formulations with no pre-modern history.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR