Poloxamer 407
AKA “Pluronic F-127, Poloxamer 407, Polyoxypropylene Polyoxyethylene Block Copolymer
Surfactant
Ingredient Facts
Poloxamer 407
AKA: Pluronic F-127, Polyoxypropylene Polyoxyethylene Block Copolymer
Surfactant · Cleansing · EWG: 2
Synthetic
Cleanser
Emulsifier
Clean
Oxirane, methyl-, polymer with oxirane (98;67)
CAS #
9003-11-6
Form
Powder
See origin →
Functions
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Emulsifying
Forces oil and water to stay mixed instead of separating into layers. The unsung hero holding your lotion together.
Cleansing Surfactant
Emulsifier
Antioxidant Protection
Reduces Inflammation
Locks In Moisture
Removes Impurities
Mixes Oil & Water
Traditional Use
Developed in the 1950s as a synthetic poloxamer surfactant widely used in cosmetics and pharmaceuticals. Functions as an emulsifier, solubilizer, and thickening agent with no traditional or historical use prior to modern chemistry.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR