Polyaminopropyl Biguanide
AKA “N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide, Lavasorb, Mediscrub, Poly (hexamethylene biguanide), Polyhexamethylene Biguanidine HCl
Synthetic
Ingredient Facts
Polyaminopropyl biguanide
AKA: N'-[6-[(N'-methylcarbamimidoyl)amino]hexyl]ethanimidamide, Lavasorb, Mediscrub, Poly (hexamethylene biguanide), Polyhexamethylene Biguanidine HCl
Synthetic · Antimicrobial · EWG: 4
Synthetic
Preservative
Synthetic
Clean
A gentle preservative that keeps our formulas fresh and effective, so your product stays safe to use from first application to last.
CAS #
32289-58-0, 27083-27-8, 28757-47-3, 133029-32-0
Form
Liquid
See origin →
Functions
Preservative
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Preserves Formula
Locks In Moisture
Fights Bacteria
Prevents microbial growth
Traditional Use
Developed as a synthetic antimicrobial preservative in the 1970s-1980s for use in cosmetics and personal care products to prevent bacterial and fungal growth.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Safe w/Qualifications
Pregnancy
Caution
CIR Safety Findings
medical-approval
all-shades-safe
Potential Sensitizer
Concentration Guide
0.1%
0%0%
Reg. Limit
EU/SCCS limit: 0.1% in cosmetic products. Opinion: SCCS/1581/16
Regulatory Status
USApermitted
EUpermitted
JAPANpermitted
CANADApermitted
Verified Feb 2026
Data: CosIng · EWG · CIR