Polyurethane-53
AKA “Polyurethane
Synthetic
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Ingredient Facts
Polyurethane-53
Synthetic · Film Forming | Nail Conditioning · EWG: 4
Plant-Derived
Occlusive
Skin Conditioner
Synthetic
Clean
A conditioning polymer that strengthens and smooths nails, helping them stay resilient and healthy-looking.
Plant-Derived
Synthetic. Polyurethane-53 is synthesized from polyols and diisocyanates, which are petroleum-derived chemical precursors. The compound is produced through step-growth polymerization, where diisocyanate monomers react with polyol compounds to form long-chain polymer chains.
Function
Film Forming | Nail Conditioning
Benefits
Nail Conditioning
Strengthens nails
Traditional Use
Synthetic polymer developed in the mid-20th century. Used in cosmetics as a film-forming and conditioning agent in hair and skin products.
Skin Types
all-skin-types
Best For
Target
General
Melanin-Rich Skin
Suitable
Pregnancy Safe
Yes
EWG Score4
CIR Safety Findings
medical-approval, all-shades-safe, Not a Sensitizer
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: CosIng · EWG · CIR