PPG-12
AKA “Polypropylene glycol 12”
Skin Conditioning
Ingredient Facts
PPG-12
AKA: Polypropylene glycol 12
Skin Conditioning · Skin Conditioning · EWG: 1
Synthetic
Skin Conditioner
Clean
Poly[oxy(methyl-1,2-ethanediyl)], .alpha.-hydro-.omega.-hydroxy- (12 mol PO average molar ratio)
CAS #
25322-69-4
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
A low-molecular-weight propylene glycol polymer developed in the mid-20th century as a humectant and solvent. It was engineered to attract and retain moisture, replacing older glycerin-based formulations with a more versatile synthetic alternative for contemporary cosmetics.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
Amended Final Report on the Safety Assessment of PPG-9-Buteth-12, PPG-12-Butheth-16, PPG-26-Buteth-26, and PPG-28-Butheth-35
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of PPG-12-Buteth-16, PPG-9-Buteth-12, PPG-26-Buteth-26 and PPG-28-Buteth-35
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Dimethicone PEG/PPG-12/4 Phosphate
European Commission
EU Cosmetic Ingredient Database (CosIng)
PEG/PPG-12/16 Dimethicone
European Commission
EU Cosmetic Ingredient Database (CosIng)
PEG/PPG-12/18 Dimethicone
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12 Butyl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12 Butyl Ether Dimethicone
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12 Dimethicone
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12-Buteth-12
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12-Buteth-16
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12-PEG-50 Lanolin
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-12-PEG-65 Lanolin Oil
European Commission
EU Cosmetic Ingredient Database (CosIng)
Dimethicone PEG/PPG-12/4 Phosphate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
PPG-12
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
PPG-12-Buteth-16
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
PPG-12-PEG-50 Lanolin
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
PPG-12-PEG-65 Lanolin Oil
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Verified Jun 2026
Data: CosIng · EWG · CIR