PPG-2 Methyl Ether
AKA “Propanol, 1(or 2)-(2-methoxymethylethoxy)-, Kino-red, RQ1X8FMQ9N, Arcosolv DPM, Glysolv DPM, Ucar solvent 2LM, Dowanol-50B, DPGME, HISOLVE DPM
Ingredient
Ingredient Facts
Ppg-2 methyl ether
AKA: Propanol, 1(or 2)-(2-methoxymethylethoxy)-, Kino-red, RQ1X8FMQ9N, Arcosolv DPM, Glysolv DPM, Ucar solvent 2LM, Dowanol-50B, DPGME, HISOLVE DPM
Ingredient · Perfuming · EWG: 5
Synthetic
Fragrance
Solvent
Not Clean
Dipropylene glycol monomethyl ether
Solubility Miscible (NIOSH, 2024)
Formula
C7H16O3
Mol. Weight
148.20
CAS #
13429-07-7, 34590-94-8
Form
Liquid
State
Dipropylene glycol methyl ether is a colorless liquid with a weak odor. (USCG, 1999)
See origin →
Functions
Perfuming
Added for scent. Can be natural or synthetic. Common irritant and allergen — one of the top reasons people react to products.
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Anti-Inflammatory
Moisturizing
Fights Acne
Adds pleasant scent
Dissolves other ingredients
Traditional Use
A synthetic propylene glycol derivative created in the 20th century for use as a humectant and solvent in cosmetics. Developed as part of the synthetic glycol family to replace traditional plant-based moisturizers.
Skin Types
all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
5
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Extended Re-review Summary: Safety Assessment of Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamines
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Aminomethylpropanol and Aminomethylpropanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Diisopropanolamine, Triisopropanolamine, Isopropanolamine, and Mixed Isopropanolamine
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Methoxyisopropanol and Methoxyisopropyl Acetate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Aminomethyl Propanol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Isopropanolamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Methoxyisopropanol
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-2 Methyl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
PPG-2 Methyl Ether Acetate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Triisopropanolamine
European Commission
EU Cosmetic Ingredient Database (CosIng)
Final report on the safety assessment of methoxyisopropanol and methoxyisopropyl acetate as used in cosmetics.
Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2008
2-Methyl-1-Phenyl-2-Propanol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Aminomethyl Propanol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Diisopropanolamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Isopropanolamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Mixed Isopropanolamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Mixed Isopropanolamines
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Phenylpropanol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Triisopropanolamine
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
2-Methoxypropanol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
Methoxyisopropanol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
β-elemene Isopropanolamine Derivative LXX-8250 Induces Apoptosis Through Impairing Autophagic Flux via PFKFB4 Repression in Melanoma Cells.
Jalal S, Zhang T, Deng J, Wang J, Xu T et al.
Frontiers in pharmacology, 2022
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Pharmacokinetics and bioavailability of diisopropanolamine (DIPA) in rats following intravenous or dermal application.
Saghir SA, Frantz SW, Spence MW, Nolan RJ, Lowe ER et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007
Fragrance material review on 2,2-dimethyl-3-phenylpropanol.
Scognamiglio J, Jones L, Letizia CS, Api AM
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR