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PPG-3 Methyl Ether
AKA “20V3X25LZO, 2-(2-(2-methoxy-1-methyl-ethoxy)-1-methyl-ethoxy)propan-1-ol, RefChem:197546, Dowanol TPM, (2-(2-METHOXYMETHYLETHOXY)METHYLETHOXY)PROPANOL, Arcosolv TPM, [2-(2-Methoxymethylethoxy)methylethoxy]propanol, O-Methyltripropylene glycol, EINECS 247-045-4”
Ingredient
Ingredient Facts
Ppg-3 methyl ether
AKA: 20V3X25LZO, 2-(2-(2-methoxy-1-methyl-ethoxy)-1-methyl-ethoxy)propan-1-ol, RefChem:197546, Dowanol TPM, (2-(2-METHOXYMETHYLETHOXY)METHYLETHOXY)PROPANOL, Arcosolv TPM, [2-(2-Methoxymethylethoxy)methylethoxy]propanol, O-Methyltripropylene glycol, EINECS 247-045-4
Ingredient · Solvent · EWG: 2
Synthetic
Solvent
Clean
[2-(2-methoxymethylethoxy)methylethoxy]propanol
Formula
C10H22O4
Mol. Weight
206.28
CAS #
25498-49-1, 37286-64-9
Form
Liquid
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Dissolves Ingredients
Locks In Moisture
Fights Bacteria
Dissolves other ingredients
Traditional Use
Synthetic humectant and solvent created mid-20th century as part of advances in polymer chemistry. Used in cosmetics for moisture retention and product consistency.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
2
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not an Irritant
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Final Report on the Safety of PPG-2 Methyl Ether, PPG-3 Methyl Ether, and PPG-2 Methyl Ether Acetate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
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PPG-3 Methyl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PPG-3 Methyl Ether
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
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Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
Robinson V, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR