Proline
AKA “L-proline, L-(-)-Proline, (2S)-pyrrolidine-2-carboxylic acid, (S)-Pyrrolidine-2-carboxylic acid, (-)-Proline, 2-pyrrolidinecarboxylic acid, (-)-(S)-Proline, (S)-2-Pyrrolidinecarboxylic acid
Synthetic
Ingredient Facts
Proline
AKA: L-proline, L-(-)-Proline, (2S)-pyrrolidine-2-carboxylic acid, (S)-Pyrrolidine-2-carboxylic acid, (-)-Proline, 2-pyrrolidinecarboxylic acid, (-)-(S)-Proline, (S)-2-Pyrrolidinecarboxylic acid
Synthetic · Hair Conditioning · EWG: 4
Synthetic
Skin Conditioner
Hair Care
Amino Acid
Synthetic
Clean
Proline is an amino acid that helps strengthen and condition hair while softening skin, leaving both feeling smoother and more supple.
Solubility 162000
Formula
C5H9NO2
Mol. Weight
115.13
CAS #
147-85-3, 609-36-9
Form
Powder
State
Dry Powder
See origin →
Functions
Hair Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
An amino acid first isolated in 1901. While not traditionally used as a standalone ingredient, proline occurs naturally in skin collagen and has been studied for its role in skin structure and wound healing.
Skin Types
all-skin-types
Best For
Dryness
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR