Propanediol
AKA “26264-14-2, Propandiol, DTXSID9074939, RefChem:9087, DTXCID7037476, Coupling Lavender Relax Premium massagelotion, Coupling Chamomile Relax Premium massagelotion, 1, 3-PROPANEDIOL (USP-RS), FEMA NO. 4753”
Ingredient
Ingredient Facts
Propanediol
AKA: 26264-14-2, Propandiol, DTXSID9074939, RefChem:9087, DTXCID7037476, Coupling Lavender Relax Premium massagelotion, Coupling Chamomile Relax Premium massagelotion, 1, 3-PROPANEDIOL (USP-RS), FEMA NO. 4753
Ingredient · Solvent · EWG: 2
Synthetic
Solvent
Clean
Cosmetics and personal care products are not required to be tested for safety before being allowed on the market. The Skin Deep® scoring system was designed to help the public understand whether a product is safe to use or whether it contains ingredients of concern.
Formula
C3H8O2
Mol. Weight
76.09
CAS #
504-63-2, 26264-14-2
Form
Liquid
See origin →
Functions
Solvent
Dissolves other ingredients so they distribute evenly in the formula. Often the invisible "base" everything else is mixed into.
Viscosity Controlling
Dissolves Ingredients
Controls Viscosity
Antioxidant Protection
Reduces Inflammation
Fights Bacteria
Dissolves other ingredients
Controls product thickness
Traditional Use
Developed in the mid-20th century as a synthetic humectant and preservative booster. Created to replace glycerin in industrial and cosmetic applications where a less viscous, more stable moisture-binding agent was needed.
Skin Types
●all-skin-types, gentle
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
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Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Safety Assessment of Tromethamine, Aminomethyl Propanediol, and Aminoethyl Propanediol as Used in Cosmetics.
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2018
Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.
Burnett CL, Bergfeld WF, Belsito DV, Klaassen CD, Marks JG Jr et al.
International journal of toxicology, 2009
Final Amended Report on the Safety Assessment of Aminomethyl Propanol and Aminomethyl Propanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Final Report on the Safety Assessment of Aminomethylpropanol and Aminomethylpropanediol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Safety Assessment of Tromethamine, Aminomethyl Propanediol and Aminoethyl Propanediol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Aminoethyl Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Butyl Ethyl Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dicaprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dicaprylate/Caprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Diisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Propanediol Dipelargonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Aminoethyl Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Aminomethyl Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Methylpropanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol Dicaprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Propanediol Dicaprylate/Caprate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Progress in 1,3-propanediol biosynthesis.
Li B, Gao W, Pan Y, Yao Y, Liu G
Frontiers in bioengineering and biotechnology, 2024
Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function.
Pinto JR, Monteiro E Silva SA, Leonardi GR
International journal of cosmetic science, 2024
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR