Propionyl Collagen Amino Acids
AKA “Hydrolyzed Collagen Propionate
Acid
Ingredient Facts
Propionyl collagen amino acids
AKA: Hydrolyzed Collagen Propionate
Acid · Skin Conditioning · EWG: 4
Synthetic
Skin Conditioner
Marine
Amino Acid
Acid
Not Clean
Condensation product of propionic acid chloride with collagen amino acids
CAS #
210545-23-6; 616-91-1; 1188-37-0; 2490-97-3; 35305-74-9
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Boosts collagen production
Locks in moisture
Traditional Use
Developed in the late 20th century as a modified protein derivative. Created as a film-forming and conditioning agent for skincare and haircare products, designed to mimic collagen's moisturizing properties.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: CosIng · EWG · CIR