Propionyl Collagen Amino Acids
AKA “Hydrolyzed Collagen Propionate
Synthetic
Ingredient Facts
Propionyl collagen amino acids
AKA: Hydrolyzed Collagen Propionate
Synthetic · Humectant · EWG: 4
Plant-Derived Synthetic
Humectant
Occlusive
Skin Conditioner
Marine
Amino Acid
Synthetic
Clean
Condensation product of propionic acid chloride with collagen amino acids Science: Functions: Skin Conditioning Safety Ratings: CIR: Safe as used
CAS #
210545-23-6; 616-91-1; 1188-37-0; 2490-97-3; 35305-74-9
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Film Forming
Creates a physical seal on skin to lock moisture in and keep irritants out. The "slugging" ingredient — barrier protection.
Boosts collagen production
Locks in moisture
Traditional Use
Developed in the late 20th century as a modified protein derivative. Created as a film-forming and conditioning agent for skincare and haircare products, designed to mimic collagen's moisturizing properties.
Skin Types
all-skin-types
Best For
Loss of Elasticity
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Insufficient
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: CosIng · EWG · CIR