Propylene Glycol Isostearate
AKA “EINECS 269-027-5, Isooctadecanoic acid, monoester with 1, 2-propanediol, RefChem:149646, DTXCID50815702, 2-hydroxypropyl 16-methylheptadecanoate, Propylene glycol monoisostearate
Synthetic
Ingredient Facts
Propylene glycol isostearate
AKA: EINECS 269-027-5, Isooctadecanoic acid, Monoester with 1, 2-propanediol, RefChem:149646, DTXCID50815702, 2-hydroxypropyl 16-methylheptadecanoate, Propylene glycol monoisostearate
Synthetic · Cleansing · EWG: 4
Plant-Derived Synthetic
Cleanser
Skin Conditioner
Synthetic
Clean
A gentle cleansing agent that removes makeup and impurities while conditioning skin. Derived from natural sources, it helps maintain skin's natural moisture barrier.
Effective at 30.15%
Formula
C21H42O3
Mol. Weight
342.60
CAS #
68171-38-0, 63799-53-1
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Locks in moisture
Traditional Use
Synthetic ester developed as a modern emollient and skin conditioning agent for cosmetics. Designed to provide smooth texture and enhanced spreadability in formulations.
Skin Types
all-skin-types
Best For
General
Melanin-Rich Skin
Suitable
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
0.3%
60.0%
0%84%
Effective Range
CIR reported use: 0.71-60 | 1-33.796 | 0.3-15
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: PubChem · CosIng · EWG · CIR