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Propylene Glycol Linolenate
AKA “propylene glycol, 2-propanediol, propane-1, 2-Propylene glycol, 2-dihydroxypropane”
Surfactant
Ingredient Facts
Propylene glycol linolenate
AKA: 2-propanediol, Propane-1, 2-Propylene glycol, 2-dihydroxypropane
Surfactant · Cleansing · EWG: 4
Synthetic
Cleanser
Skin Conditioner
Not Clean
9,12,15-Octadecatrienoic acid, 2-hydroxypropyl ester
Effective at 1.0%
Formula
C3H8O2
Mol. Weight
76.09
CAS #
57-55-6
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Cleansing
Makes oil and water mix so dirt, makeup, and sunscreen can actually be washed away. The reason your face wash foams.
Locks in moisture
Traditional Use
Synthetic ester combining propylene glycol with linolenic acid, developed for cosmetic formulations. Created to provide emollient and skin-conditioning properties similar to plant-based oils.
Skin Types
●all-skin-types
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Concentration Guide
9.9e-05%
2.0%
0%14%
Effective Range
CIR reported use: 0.000099-2
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
NTP toxicology and carcinogensis studies of dipropylene glycol (CAS No. 25265-71-8) in F344/N rats and B6C3F1 mice (drinking water studies).
National Toxicology Program technical report series, 2004
→
Effect of hydration on the structure of non aqueous ethyl cellulose/propylene glycol dicaprylate gels.
Bruno L, Kasapis S, Heng PW
International journal of biological macromolecules, 2012
→
Propylene glycol dermatitis.
J M Catanzaro, J G Smith
Journal of the American Academy of Dermatology, 1991
→
Propylene glycol dermatitis.
J M Catanzaro, J G Smith
Journal of the American Academy of Dermatology, 1991
→
Propylene glycol dermatitis.
J M Catanzaro, J G Smith
Journal of the American Academy of Dermatology, 1991
→
Addendum to the Final Report on the Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol (JEPT 4(4) 47-61 1980)
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report of the Safety Assessment for 2-Bromo-2-Nitropropane-1,3-Diol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Butylene Glycol, Hexylene Glycol, Ethoxydiglycol, and Dipropylene Glycol
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of PEG-25 Propylene Glycol Stearate, PEG-75 Propylene Glycol, PEG-120 Propylene Glycol Stearate, PEG-10 Propylene Glycol, PEG-8 Propylene Glycol Cocoate, and PEG-
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Propylene Glycol (PG) Dicaprylate, PG Dicaprylate/Dicaprate, PG Dicocoate, PG Dipelargonate, PG Isostearate, PG Laurate, PG Myristate, PG Oleate, PG Oleate SE,
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Propylene Glycol and Polypropylene Glycols
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Propylene Glycol Stearate and Propylene Glycol Stearate Self-Emulsifying
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report: Amended Safety Assessment of PEG Propylene Glycol Derivatives as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report: Safety Assessment of Propylene Glycol Esters as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Revised Tentative Report: Amended Safety Assessment of 2-Bromo-2-Nitropropane-1,3-Diol as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Propylene Glycol, Tripropylene Glycol and PPGs as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
2-Bromo-2-Nitropropane-1,3-Diol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Almond Oil Propylene Glycol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Apricot Kernel Oil Propylene Glycol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Avocado Oil Propylene Glycol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Olive Oil Propylene Glycol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-10 Propylene Glycol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-120 Propylene Glycol Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-25 Propylene Glycol Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-55 Propylene Glycol Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-6 Propylene Glycol Caprylate/Caprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-75 Propylene Glycol Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
PEG-8 Propylene Glycol Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Alginate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Behenate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Butyl Ether
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Capreth-4
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Caprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Cocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dicaprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dicaproate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dicaprylate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dicaprylate/Dicaprate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dicocoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Diethylhexanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Diisononanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Diisostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dilaurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dioleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Dipelargonate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Distearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Diundecanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Heptanoate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Isodeceth-12
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Isodeceth-4
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Isostearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Laurate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Laureth-6
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Linoleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Linolenate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Myristate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Oleate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Oleate SE
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Oleth-5
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Soyate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Stearate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol Stearate SE
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Propylene Glycol/Sebacic Acid/Trimellitic Anhydride Copolymer
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Soybean Oil Propylene Glycol Esters
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Tripropylene Glycol
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
2-Bromo-2-Nitropropane-1,3-Diol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Dipropylene Glycol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-25 Propylene Glycol Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-55 Propylene Glycol Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PEG-8 Propylene Glycol Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
PROPANE-1
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Alginate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Butyl Ether
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Caprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Cocoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Dicaprate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Dicaprylate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Dicaprylate/Dicaprate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Diethylhexanoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Dipelargonate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Heptanoate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Isostearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Laurate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Oleate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Oleate SE
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Stearate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Propylene Glycol Stearate SE
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Tripropylene Glycol
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al.
International journal of toxicology, 2012
→
The Additive Influence of Propane-1,2-Diol on SDS Micellar Structure and Properties.
Gudelj M, Šurina P, Jurko L, Prkić A, Bošković P
Molecules (Basel, Switzerland), 2021
→
2-Bromo-2-nitropropane-1,3-diol
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
Urinary excretion of propylene glycol butyl ether (PGBE) and propylene glycol methyl ether (PGME) in healthy human participants and workers.
Hopf NB, Kaspar S, Berthet A, Hechon J, Pache J et al.
International journal of hygiene and environmental health, 2026
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Propylene Glycol.
Jacob SE, Scheman A, McGowan MA
Dermatitis : contact, atopic, occupational, drug, 2018
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
Final report on the safety assessment of PEG-25 propylene glycol stearate, PEG-75 propylene glycol stearate, PEG-120 propylene glycol stearate, PEG-10
Johnson W Jr, Cosmetic Ingredient Review Expert Panel
International journal of toxicology, 2001
→
The Inhibitory Effect of Propylene Glycol Alginate Sodium Sulfate on Fibroblast Growth Factor 2-Mediated Angiogenesis and Invasion in Murine Melanoma
Ma H, Qiu P, Xu H, Xu X, Xin M et al.
Marine drugs, 2019
→
Propylene glycol, skin sensitisation and allergic contact dermatitis: A scientific and regulatory conundrum.
Pemberton MA, Kimber I
Regulatory toxicology and pharmacology : RTP, 2023
→
Kitty Litter Dermatitis from-Bromo-2-Nitropropane-1,3-Diol.
Sullenbarger JW, Hensley B, Travers JB
Skinmed, 2017
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR