Psicose
AKA “Erythrohexulose, Pseudofructose, Allulose, 23140-52-5, ribo-2-Hexulose, KRF88IOA7T, RefChem:930198, GlyTouCan:G67077DJ, CHEBI:33951”
Humectant
Ingredient Facts
Psicose
AKA: Erythrohexulose, Pseudofructose, Allulose, 23140-52-5, Ribo-2-Hexulose, KRF88IOA7T, RefChem:930198, GlyTouCan:G67077DJ, CHEBI:33951
Humectant · Humectant · EWG: 4
Synthetic
Humectant
Skin Conditioner
Not Clean
Allulose,6-Pentahydroxy-2-hexanone
Formula
C6H12O6
Mol. Weight
180.16
CAS #
23140-52-5
Form
Powder
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks In Moisture
Traditional Use
A rare sugar alcohol discovered and developed in the late 20th century as a low-calorie sweetener. Used in modern cosmetics as a humectant and skin conditioning agent, offering benefits similar to traditional glycerin.
Skin Types
●all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
EWG
4
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 100%. Source: CIR Safety Assessment (CIR Seq 815).
Regulatory Agencies
Safety Assessment of Anhydrogalactose,Anhydroglucitol, Anhydroxylitol, Arabinose,Psicose, Saccharide Hydrolysate, andSaccharide Isomerate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Psicose
European Commission
EU Cosmetic Ingredient Database (CosIng)
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR