Saccharide Isomerate
AKA “Carbohydrate polymer, Humectant
Humectant
Ingredient Facts
Saccharide isomerate
AKA: Carbohydrate polymer, Humectant
Humectant · Humectant · EWG: 1
Synthetic
Humectant
Amino Acid
Clean
Saccharides, isomerised
CAS #
100843-69-4
Form
Liquid
See origin →
Functions
Humectant
A moisture magnet. Pulls water from the air and deeper skin layers up to the surface to keep skin plump and hydrated.
Locks In Moisture
Traditional Use
A modern humectant ingredient developed in the late 20th century through chemical isomerization of sugars. Designed to improve skin hydration and texture in contemporary skincare formulations.
Skin Types
all-skin-types
Best For
Dehydration
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
medical-approval
all-shades-safe
Phototoxicity Concern
Concentration Guide
Dermal absorption: 100%. Source: CIR Safety Assessment (CIR Seq 815).
Regulatory Status
USApermitted
EUrestricted
JAPANrestricted
CANADArestricted
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Safety Assessment of Anhydrogalactose,Anhydroglucitol, Anhydroxylitol, Arabinose,Psicose, Saccharide Hydrolysate, andSaccharide Isomerate as Used in Cosmetics
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
Saccharide Isomerate
European Commission
EU Cosmetic Ingredient Database (CosIng)
Saccharide Isomerate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Safety Assessment of Anhydrogalactose, Anhydroglucitol, Anhydroxylitol, Arabinose, Psicose, Saccharide Hydrolysate, and Saccharide Isomerate as Used i
Johnson W Jr, Bergfeld WF, Belsito DV, Cohen DE, Klaassen CD et al.
International journal of toxicology, 2025
Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population.
Martin E, Zhang A, Campiche R
Journal of cosmetic dermatology, 2023
Verified Jun 2026
Data: CosIng · EWG · CIR