Silybum marianum ethyl ester
AKA “Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Synthetic
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Ingredient Facts
Silybum marianum ethyl ester
AKA: Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Synthetic · Skin Conditioning | Antioxidant | Soothing · EWG: 4
Plant-Derived
Antioxidant
Soothing
Skin Conditioner
Synthetic
Clean
Milk thistle seed extract that helps condition and soften skin. This Mediterranean plant has been treasured for centuries for its nourishing properties.
Family
Asteraceae (Daisy family)
Plant Part
Seed
Lifeform
Annual or biennial
Climate
Subtropical
CAS #
84604-20-6
Form
Liquid
Plant-Derived
Botanical-Derived Synthetic. Native to Mediterranean, Europe. Derived from milk thistle seeds (Silybum marianum), a plant native to the Mediterranean region in the Asteraceae family. Produced through esterification of milk thistle seed extract compounds with ethanol to create the ethyl ester form.
Plant Source
Asteraceae (Daisy family)
Plant Part
Seed
Function
Skin Conditioning | Antioxidant | Soothing
Benefits
Locks in moisture
Traditional Use
Milk thistle (Silybum marianum) has been used in European and traditional medicine since ancient Greece for liver and skin health. The ethyl ester form is a modern extraction designed to preserve the plant's active silymarin compounds.
Skin Types
all-skin-types
Best For
Target
Irritation
Melanin-Rich Skin
Suitable
Pregnancy Safe
Caution
EWG Score4
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Feb 2026
Data: Kew POWO · CosIng · EWG · CIR