Silybum marianum ethyl ester
AKA “Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Skin Conditioning
Ingredient Facts
Silybum marianum ethyl ester
AKA: Silimarin, Silybin, Flavobin Spofa, Silymarin (>80%), Silibin
Skin Conditioning · Skin Conditioning · EWG: 4
Plant-Derived Synthetic
Skin Conditioner
Not Clean
Silybum Marianum Ethyl Ester is the ethyl ester of the fatty acids derived from the oil of the Lady's Thistle, Silybum marianum (L.), Asteraceae
CAS #
84604-20-6
Form
Liquid
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Milk thistle (Silybum marianum) has been used in European and traditional medicine since ancient Greece for liver and skin health. The ethyl ester form is a modern extraction designed to preserve the plant's active silymarin compounds.
Skin Types
all-skin-types
Best For
Irritation
Pregnancy & Breastfeeding Safe
Caution
EWG
4
CIR
Insufficient
Pregnancy
Caution
CIR Safety Findings
all-shades-safe
Regulatory Status
USAunder review
EUrestricted
JAPANrestricted
CANADArestricted
Verified Jun 2026
Data: Kew POWO · CosIng · EWG · CIR