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Silybum marianum seed oil
AKA “SILYMARIN, 65666-07-1, Silimarin, 3, 5, 7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2, 3-dihydro-1, 4-benzodioxin-6-yl]-2, 3-dihydrochromen-4-one, 7-trihydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2, 4-benzodioxin-6-yl)-2, RefChem:931755, DTXSID5023580, 613-830-9, Silybin, 84604-20-6”
Oil
Ingredient Facts
Silybum marianum seed oil
AKA: SILYMARIN, 65666-07-1, Silimarin, 3, 5, 7-trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2, 3-dihydro-1, 4-benzodioxin-6-yl]-2, 3-dihydrochromen-4-one, 7-trihydroxy-2-(3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2, 4-benzodioxin-6-yl)-2, RefChem:931755, DTXSID5023580, 613-830-9, Silybin, 84604-20-6
Oil · Skin Conditioning · EWG: 1
Plant-Derived
Skin Conditioner
Clean
Silybum Marianum Seed Oil is the fixed oil expressed from the seeds of the Lady's Thistle, Silybum marianum (L.), Asteraceae
Family
Asteraceae (Daisy family)
Plant Part
Seed
Lifeform
Annual or biennial
Climate
Subtropical
Formula
C25H22O10
Mol. Weight
482.40
CAS #
84604-20-6
Form
Oil
See origin →
Functions
Skin Conditioning
A catch-all term for ingredients that improve how skin looks and feels — softer, smoother, more supple. The workhorse behind most moisturizers.
Locks in moisture
Traditional Use
Milk thistle has been used in European herbal medicine since ancient times to support liver health and skin healing; the seed oil is used traditionally for anti-inflammatory and antioxidant properties to protect and soothe irritated skin.
Skin Types
●all-skin-types
Best For
Dryness
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe as used
Pregnancy
Yes
CIR Safety Findings
Not a Sensitizer
medical-approval
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Verified Jun 2026
Data: Kew POWO · PubChem · CosIng · EWG · CIR