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sodium anisate
AKA “536-45-8, sodium p-anisate, sodium p-methoxybenzoate, UNII-F9WFJ28MV9, F9WFJ28MV9, Benzoic acid, 4-methoxy-, sodium salt, EINECS 208-634-1, DTXSID00201818, RefChem:183779”
Ingredient
Ingredient Facts
Sodium anisate
AKA: 536-45-8, Sodium p-anisate, Sodium p-methoxybenzoate, UNII-F9WFJ28MV9, F9WFJ28MV9, Benzoic acid, 4-methoxy-, Sodium salt, EINECS 208-634-1, DTXSID00201818, RefChem:183779
Ingredient · Antimicrobial · EWG: 1
Synthetic
Preservative
Safety Concern
Clean
Sodium anisate
Formula
C8H7NaO3
Mol. Weight
174.13
CAS #
536-45-8
Form
Powder
See origin →
Functions
Antimicrobial
Keeps your product from growing bacteria, mold, or yeast. Without these, that jar of cream becomes a petri dish in about a week.
Flavouring
Ph Adjusters
Fights Bacteria
Traditional Use
A synthetic preservative developed in the 20th century derived from anise (anethole); created to provide antimicrobial protection in cosmetics as a safer alternative to older chemical preservatives.
Skin Types
●all-skin-types, gentle
Best For
General
Pregnancy & Breastfeeding Safe
Yes
EWG
1
CIR
Safe
Pregnancy
Yes
CIR Safety Findings
Not Phototoxic
ewg-1
pregnancy-nursing-safe
all-shades-safe
Regulatory Status
USA✔ permitted
EU⚠ restricted
JAPAN⚠ restricted
CANADA⚠ restricted
Clean-ical Formulations AM + PM Serum Duo
Odacité
 →
Derm-Restore Super Serum • Edelweiss Extrême® • Peptides + Carnosine
Odacité
 →
Edelweiss Extrême® • Repair + Restore Set
Odacité
 →
Sun Defense Performance Duo • SPF 50 + Super Serum
Odacité
 →
Anti-aging Dream Duo • SPF 50 + Retinol
Odacité
 →
Bioactive Renew Supreme Cream • Edelweiss Extrême® • Peptides + Carnosine
Odacité
 →
Edelweiss Extrême® Skin Barrier Set
Odacité
 →
Age-Defying Fundamentals
Odacité
 →
Day & Night Eye Care Duo
Odacité
 →
Sun Damage Defense Duo • SPF 50 + Vitamin C
Odacité
 →
Anti Aging Eye & Sun Defense Duo
Odacité
 →
SPF 50 Color Balm Duo
Odacité
 →
SPF 50 Tinted Sunscreen & Color Balm Duo
Odacité
 →
Winter Renewal Ritual
Odacité
 →
Skin Perfecting Skincare Set
Acure
 →
AI Peptide Serum
Acure
 →
The Firm & Smooth Serum Duo
Acure
 →
AI Peptide Serum Duo
Acure
 →
Radically Rejuvenating Dual Phase Bakuchiol Serum Set
Acure
 →
The "New Skin" Gift Set: Zombie Cell Clarifying System
Acure
 →
The Texture Repair Set
Acure
 →
Zombie Cell Clarifying System
Acure
 →
Zombie Cell Clarifying Serum Mini
Acure
 →
Botanical D Moisture Mist
One Love Organics
 →
Botanical D Moisture Mist - 3 Pack
One Love Organics
 →
Radiance Boosting Starter Set
Goldfaden MD
 →
Radiance Repair Trio
Goldfaden MD
 →
Middlemist Seven™ Cream Cleanser Mini
Pai Skincare
 →
Phaze™ Gel Cleanser
Pai Skincare
 →
Gentle Genius™ Barrier Care Rapid Rescue Hand Cream
Pai Skincare
 →
The Gemini™ Stretch Mark System
Pai Skincare
 →
Phaze™ Gel Cleanser Mini
Pai Skincare
 →
The Rosehip Ritual
Pai Skincare
 →
Easy Calm, Easy Glow Gift Set
Pai Skincare
 →
Retinol Alternative Cream
Indie Lee
 →
I-Waken Eye Serum
Indie Lee
 →
Serum For Days! Trio
Indie Lee
 →
Golden Hour Recovery Cream
Ursa Major
 →
Golden Hour Recovery Cream | Ursa Major Skincare
Ursa Major
 →
Fortifying Gel Moisturizer
Ursa Major
 →
Brighten Up Vitamin C Serum
Ursa Major
 →
Botanic Buzz Hand Cream
Ursa Major
 →
Anti-Aging Sea Serum - 0.19 fl oz
OSEA
 →
Water-Lock Moisturizer - 10ML – Tata Harper Skincare
Tata Harper Skincare
 →
Water-Lock Moisturizer
Tata Harper Skincare
 →
Tata's Daily Essentials
Tata Harper Skincare
 →
Superkind Softening Cleanser
Tata Harper Skincare
 →
Superkind Fortifying Moisturizer
Tata Harper Skincare
 →
Superkind Fortifying Moisturizer - 10ML – Tata Harper Skincare
Tata Harper Skincare
 →
Crème Riche
Tata Harper Skincare
 →
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Effects of Sodium Salts of Fatty Acids and Their Derivatives on Skin Permeation of Cromolyn Sodium.
Akinbote OE, Verana G, Dandekar AA, Tijani AO, Mishra D et al.
AAPS PharmSciTech, 2023
→
Benzyl Alcohol, Benzoic Acid, Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of 4-Methoxy-m-Phenylenediamine, 4-Methoxy-m-Phenylenediamine Sulfate, and 4-Methoxy-m-Phenylenediamine-HCI
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Final Report on the Safety Assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its Salts, and Benzyl Benzoate
Cosmetic Ingredient Review (CIR) Expert Panel
International Journal of Toxicology
→
4-Hydroxybenzoic acid rescues multisystemic disease and perinatal lethality in a mouse model of mitochondrial disease.
Corral-Sarasa J, Martínez-Gálvez JM, González-García P, Wendling O, Jiménez-Sánchez L et al.
Cell reports, 2024
→
4-Hydroxybenzoic Acid
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
sodium anisate
European Commission
EU Cosmetic Ingredient Database (CosIng)
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
Benzoic acid and its derivatives as naturally occurring compounds in foods and as additives: Uses, exposure, and controversy.
Del Olmo A, Calzada J, Nuñez M
Critical reviews in food science and nutrition, 2017
→
4-Hydroxybenzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
Benzoic Acid
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
sodium anisate
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
SODIUM SALT
Environmental Working Group (EWG)
EWG Skin Deep Cosmetics Database
→
4-Methoxy-m-phenylenediamine and its sulfate salts
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
4-Methoxy-m-phenylenediamine-HCl
Health Canada
Health Canada Cosmetic Ingredient Hotlist
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Safety Assessment of Benzyl Alcohol, Benzoic Acid and its...
Wilbur Johnson, Wilma F Bergfeld, Donald V Belsito, Ronald A Hill, Curtis D Klaassen, Daniel C Liebler + 5 more
International journal of toxicology, 2017
→
Verified Jun 2026
Data: PubChem · CosIng · EWG · CIR